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Somatic alteration and depleted nuclear expression of BAP1 in human esophageal squamous cell carcinoma

BRCA1-associated protein 1 (BAP1) is a deubiquitinating enzyme that is involved in the regulation of cell growth. Recently, many somatic and germline mutations of BAP1 have been reported in a broad spectrum of tumors. In this study, we identified a novel somatic non-synonymous BAP1 mutation, a pheny...

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Detalles Bibliográficos
Autores principales: Mori, Takahiro, Sumii, Makiko, Fujishima, Fumiyoshi, Ueno, Kazuko, Emi, Mitsuru, Nagasaki, Masao, Ishioka, Chikashi, Chiba, Natsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582980/
https://www.ncbi.nlm.nih.gov/pubmed/26081045
http://dx.doi.org/10.1111/cas.12722