Oncogenic activity of BIRC2 and BIRC3 mutants independent of nuclear factor-κB-activating potential

BIRC2 and BIRC3 are closely related members of the inhibitor of apoptosis (IAP) family of proteins and play pivotal roles in regulation of nuclear factor-κB (NF-κB) signaling and apoptosis. Copy number loss for and somatic mutation of BIRC2 and BIRC3 have been frequently detected in lymphoid maligna...

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Detalles Bibliográficos
Autores principales: Yamato, Azusa, Soda, Manabu, Ueno, Toshihide, Kojima, Shinya, Sonehara, Kyuto, Kawazu, Masahito, Sai, Eirin, Yamashita, Yoshihiro, Nagase, Takahide, Mano, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582982/
https://www.ncbi.nlm.nih.gov/pubmed/26094954
http://dx.doi.org/10.1111/cas.12726

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