Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes

Insulin signaling augments glucose transport by regulating glucose transporter 4 (GLUT4) trafficking from specialized intracellular compartments, termed GLUT4 storage vesicles (GSVs), to the plasma membrane. Proteomic analysis of GSVs by mass spectrometry revealed enrichment of 59 proteins in these...

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Detalles Bibliográficos
Autores principales: Fazakerley, Daniel J., Naghiloo, Sheyda, Chaudhuri, Rima, Koumanov, Françoise, Burchfield, James G., Thomas, Kristen C., Krycer, James R., Prior, Matthew J., Parker, Ben L., Murrow, Beverley A., Stöckli, Jacqueline, Meoli, Christopher C., Holman, Geoffrey D., James, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583025/
https://www.ncbi.nlm.nih.gov/pubmed/26240143
http://dx.doi.org/10.1074/jbc.M115.657361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583025/
https://www.ncbi.nlm.nih.gov/pubmed/26240143
http://dx.doi.org/10.1074/jbc.M115.657361

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