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Delivering HIV Gagp24 to DCIR Induces Strong Antibody Responses In Vivo
Targeting dendritic cell-specific endocytic receptors using monoclonal antibodies fused to desired antigens is an approach widely used in vaccine development to enhance the poor immunogenicity of protein-based vaccines and to induce immune responses. Here, we engineered an anti-human DCIR recombinan...
Autores principales: | Flamar, Anne-Laure, Contreras, Vanessa, Zurawski, Sandra, Montes, Monica, Dereuddre-Bosquet, Nathatlie, Martinon, Frédéric, Banchereau, Jacques, Le Grand, Roger, Zurawski, Gerard, Levy, Yves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583231/ https://www.ncbi.nlm.nih.gov/pubmed/26407317 http://dx.doi.org/10.1371/journal.pone.0135513 |
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