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Deep Sequencing for Evaluation of Genetic Stability of Influenza A/California/07/2009 (H1N1) Vaccine Viruses

Virus growth during influenza vaccine manufacture can lead to mutations that alter antigenic properties of the virus, and thus may affect protective potency of the vaccine. Different reassortants of pandemic "swine" H1N1 influenza A vaccine (121XP, X-179A and X-181) viruses as well as wild...

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Detalles Bibliográficos
Autores principales:	Majid, Laassri, Zagorodnyaya, Tatiana, Plant, Ewan P., Petrovskaya, Svetlana, Bidzhieva, Bella, Ye, Zhiping, Simonyan, Vahan, Chumakov, Konstantin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583247/ https://www.ncbi.nlm.nih.gov/pubmed/26407068 http://dx.doi.org/10.1371/journal.pone.0138650

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