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Aberrantly Expressed OTX Homeobox Genes Deregulate B-Cell Differentiation in Hodgkin Lymphoma

In Hodgkin lymphoma (HL) we recently reported that deregulated homeobox gene MSX1 mediates repression of the B-cell specific transcription factor ZHX2. In this study we investigated regulation of MSX1 in this B-cell malignancy. Accordingly, we analyzed expression and function of OTX homeobox genes w...

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Detalles Bibliográficos
Autores principales: Nagel, Stefan, Ehrentraut, Stefan, Meyer, Corinna, Kaufmann, Maren, Drexler, Hans G., MacLeod, Roderick A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583255/
https://www.ncbi.nlm.nih.gov/pubmed/26406991
http://dx.doi.org/10.1371/journal.pone.0138416

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