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The Matricellular Protein CCN1 Promotes Mucosal Healing in Murine Colitis through IL-6
The matricellular protein CCN1 (CYR61) is known to function in wound healing and is upregulated in colons of patients with Crohn’s disease and ulcerative colitis, yet its specific role in colitis is unknown. Here we have used Ccn1(dm/dm) knockin mice expressing a CCN1 mutant unable to bind integrins...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583322/ https://www.ncbi.nlm.nih.gov/pubmed/25807183 http://dx.doi.org/10.1038/mi.2015.19 |