Cargando…

Trypsin, Tryptase, and Thrombin Polarize Macrophages towards a Pro-Fibrotic M2a Phenotype

For both wound healing and the formation of a fibrotic lesion, circulating monocytes enter the tissue and differentiate into fibroblast-like cells called fibrocytes and pro-fibrotic M2a macrophages, which together with fibroblasts form scar tissue. Monocytes can also differentiate into classically a...

Descripción completa

Detalles Bibliográficos
Autores principales:	White, Michael J. V., Gomer, Richard H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583378/ https://www.ncbi.nlm.nih.gov/pubmed/26407067 http://dx.doi.org/10.1371/journal.pone.0138748

Ejemplares similares

Tryptase and Exogenous Trypsin: Mechanisms and Ophthalmic Applications
por: Ma, Chao, et al.
Publicado: (2023)

Trypsin Potentiates Human Fibrocyte Differentiation
por: White, Michael J. V., et al.
Publicado: (2013)

Urokinase Plasminogen Activator Induces Pro-Fibrotic/M2 Phenotype in Murine Cardiac Macrophages
por: Meznarich, Jessica, et al.
Publicado: (2013)

Foam Cell Formation In Vivo Converts Macrophages to a Pro-Fibrotic Phenotype
por: Thomas, Anita C., et al.
Publicado: (2015)

MSC−sEV Treatment Polarizes Pro−Fibrotic M2 Macrophages without Exacerbating Liver Fibrosis in NASH
por: Zhang, Bin, et al.
Publicado: (2023)

KINETICS OF THROMBIN INACTIVATION AS INFLUENCED BY PHYSICAL CONDITIONS, TRYPSIN, AND SERUM
por: Glazko, Anthony J., et al.
Publicado: (1940)

Periostin—An inducer of pro-fibrotic phenotype in monocytes and monocyte-derived macrophages in systemic sclerosis
por: Suzuki, Mao, et al.
Publicado: (2023)

Interstitial flow promotes macrophage polarization toward an M2 phenotype
por: Li, Ran, et al.
Publicado: (2018)

Overexpression of OSM and IL-6 impacts the polarization of pro-fibrotic macrophages and the development of bleomycin-induced lung fibrosis
por: Ayaub, Ehab A., et al.
Publicado: (2017)

A2BAR Antagonism Decreases the Glomerular Expression and Secretion of Chemoattractants for Monocytes and the Pro-Fibrotic M2 Macrophages Polarization during Diabetic Nephropathy
por: Torres-Arévalo, Ángelo, et al.
Publicado: (2023)

The pro-fibrotic and anti-inflammatory foam cell macrophage paradox
por: Thomas, Anita C., et al.
Publicado: (2015)

Macrophage polarization toward M1 phenotype in T cell transfer colitis model
por: Ebihara, Shin, et al.
Publicado: (2023)

Pro-fibrotic SNPs
por: Maxmen, Amy
Publicado: (2009)

Adipose-Derived Stem Cells from Obese Donors Polarize Macrophages and Microglia toward a Pro-Inflammatory Phenotype
por: Harrison, Mark A. A., et al.
Publicado: (2020)

Human Macrophages Polarized by Interaction with Apoptotic Cells Produce Fibrosis-Associated Mediators and Enhance Pro-Fibrotic Activity of Dermal Fibroblasts In Vitro
por: Maksimova, Aleksandra, et al.
Publicado: (2023)

Polymer-Functionalized Mitochondrial Transplantation to Fibroblasts Counteracts a Pro-Fibrotic Phenotype
por: Baudo, Gherardo, et al.
Publicado: (2023)

Alpha fetoprotein promotes polarization of macrophages towards M2-like phenotype and inhibits macrophages to phagocytize hepatoma cells
por: Zhang, Minni, et al.
Publicado: (2023)

Mast cell tryptase and asthma
por: Zhang, M-Q., et al.
Publicado: (1997)

Pro-fibrotic M2 macrophage markers may increase the risk for COVID19 in type 2 diabetes with obesity()()
por: Moin, Abu Saleh Md, et al.
Publicado: (2020)

The Epigenomic Landscape: A Cornerstone of Macrophage Phenotype Regulation in the Fibrotic Lung
por: Ballinger, Megan N., et al.
Publicado: (2021)

Thrombin-induced CCN2 expression as a target for anti-fibrotic therapy in scleroderma
por: Leask, Andrew
Publicado: (2009)

Enterococcus faecalis shifts macrophage polarization toward M1-like phenotype with an altered cytokine profile
por: Mohamed Elashiry, Mohamed, et al.
Publicado: (2021)

TNFSF15 facilitates differentiation and polarization of macrophages toward M1 phenotype to inhibit tumor growth
por: Zhao, Can-Can, et al.
Publicado: (2022)

Decreased ferroportin in hepatocytes promotes macrophages polarize towards an M2-like phenotype and liver fibrosis
por: Cai, Chengyuan, et al.
Publicado: (2021)

TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype
por: Zhang, Fan, et al.
Publicado: (2016)

Macrophages During the Fibrotic Process: M2 as Friend and Foe
por: Braga, Tarcio Teodoro, et al.
Publicado: (2015)

The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases
por: Wermuth, Peter J, et al.
Publicado: (2015)

17 A Tissue-engineered Bi-layer Skin Substitute Polarizes Macrophages Towards an M2 Phenotype
por: Hernaez-Estrada, Beatriz, et al.
Publicado: (2022)

Hypoxia Promotes a Mixed Inflammatory-Fibrotic Macrophages Phenotype in Active Sarcoidosis
por: Jeny, Florence, et al.
Publicado: (2021)

New Biomarkers in Anaphylaxis (Beyond Tryptase)
por: Galvan-Blasco, P., et al.
Publicado: (2022)

Macrophage polarization toward M1 phenotype through NF-κB signaling in patients with Behçet’s disease
por: Wu, Xiuhua, et al.
Publicado: (2022)

Genetic Deletion of Polo-Like Kinase 2 Induces a Pro-Fibrotic Pulmonary Phenotype
por: Kant, Theresa A., et al.
Publicado: (2021)

Ionizing radiation modulates human macrophages towards a pro-inflammatory phenotype preserving their pro-invasive and pro-angiogenic capacities
por: Teresa Pinto, Ana, et al.
Publicado: (2016)

Atrial Tissue Pro‐Fibrotic M2 Macrophage Marker CD163+, Gene Expression of Procollagen and B‐Type Natriuretic Peptide
por: Watson, Chris J., et al.
Publicado: (2020)

ProAlanase is an Effective Alternative to Trypsin for Proteomics Applications and Disulfide Bond Mapping
por: Samodova, Diana, et al.
Publicado: (2020)

Obesity/Type II diabetes alters macrophage polarization resulting in a fibrotic tendon healing response
por: Ackerman, Jessica E., et al.
Publicado: (2017)

Trypsin may induce cytokine storm in M1 macrophages, resulting in critical coronavirus disease
por: Chen, Hongyu, et al.
Publicado: (2022)

Inhibition of Sprouty2 polarizes macrophages toward an M2 phenotype by stimulation with interferon γ and Porphyromonas gingivalis lipopolysaccharide
por: Atomura, Ryo, et al.
Publicado: (2016)

Pravastatin polarizes the phenotype of macrophages toward M2 and elevates serum cholesterol levels in apolipoprotein E knockout mice
por: Zhang, Xiaoling, et al.
Publicado: (2018)

Carbon Monoxide Regulates Macrophage Differentiation and Polarization toward the M2 Phenotype through Upregulation of Heme Oxygenase 1
por: Kang, In-Soon, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_28jc6c4mtlt5mgcinrrf8a8llh