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Inactivation of the Autolysis-Related Genes lrgB and yycI in Staphylococcus aureus Increases Cell Lysis-Dependent eDNA Release and Enhances Biofilm Development In Vitro and In Vivo
Staphylococcus aureus ica-independent biofilms are multifactorial in nature, and various bacterial proteins have been associated with biofilm development, including fibronectin-binding proteins A and B, protein A, surface protein SasG, proteases, and some autolysins. The role of extracellular DNA (e...
Autores principales: | Beltrame, Cristiana Ossaille, Côrtes, Marina Farrel, Bonelli, Raquel Regina, Côrrea, Ana Beatriz de Almeida, Botelho, Ana Maria Nunes, Américo, Marco Antônio, Fracalanzza, Sérgio Eduardo Longo, Figueiredo, Agnes Marie Sá |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583396/ https://www.ncbi.nlm.nih.gov/pubmed/26406329 http://dx.doi.org/10.1371/journal.pone.0138924 |
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