HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins

The pathogenesis of peripheral neuropathies in adults is linked to maintenance mechanisms that are not well understood. Here, we elucidate a novel critical maintenance mechanism for Schwann cell (SC)–axon interaction. Using mouse genetics, ablation of the transcriptional regulators histone deacetyla...

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Detalles Bibliográficos
Autores principales: Brügger, Valérie, Engler, Stefanie, Pereira, Jorge A., Ruff, Sophie, Horn, Michael, Welzl, Hans, Münger, Emmanuelle, Vaquié, Adrien, Sidiropoulos, Páris N. M., Egger, Boris, Yotovski, Peter, Filgueira, Luis, Somandin, Christian, Lühmann, Tessa C., D’Antonio, Maurizio, Yamaguchi, Teppei, Matthias, Patrick, Suter, Ueli, Jacob, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583457/
https://www.ncbi.nlm.nih.gov/pubmed/26406915
http://dx.doi.org/10.1371/journal.pbio.1002258

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