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Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci

The growing availability of high-quality genomic annotation has increased the potential for mechanistic insights when the specific variants driving common genome-wide association signals are accurately localized. A range of fine-mapping strategies have been advocated, and specific successes reported...

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Detalles Bibliográficos
Autores principales: van de Bunt, Martijn, Cortes, Adrian, Brown, Matthew A., Morris, Andrew P., McCarthy, Mark I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583479/
https://www.ncbi.nlm.nih.gov/pubmed/26406328
http://dx.doi.org/10.1371/journal.pgen.1005535

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