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Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci
The growing availability of high-quality genomic annotation has increased the potential for mechanistic insights when the specific variants driving common genome-wide association signals are accurately localized. A range of fine-mapping strategies have been advocated, and specific successes reported...
Autores principales: | van de Bunt, Martijn, Cortes, Adrian, Brown, Matthew A., Morris, Andrew P., McCarthy, Mark I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583479/ https://www.ncbi.nlm.nih.gov/pubmed/26406328 http://dx.doi.org/10.1371/journal.pgen.1005535 |
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