FOXM1 is overexpressed in B-acute lymphoblastic leukemia (B-ALL) and its inhibition sensitizes B-ALL cells to chemotherapeutic drugs

The Forkhead box protein M1 (FOXM1) is a transcription factor that plays a central role in the regulation of cell cycle, proliferation, DNA repair, and apoptosis. FOXM1 is overexpressed in many human tumors and its upregulation has been linked to high proliferation rates and poor prognosis. We there...

Descripción completa

Detalles Bibliográficos
Autores principales: CONSOLARO, FRANCESCA, BASSO, GIUSEPPE, GHAEM-MAGAMI, SADAF, LAM, ERIC W.-F., VIOLA, GIAMPIETRO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583527/
https://www.ncbi.nlm.nih.gov/pubmed/26316295
http://dx.doi.org/10.3892/ijo.2015.3139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583527/
https://www.ncbi.nlm.nih.gov/pubmed/26316295
http://dx.doi.org/10.3892/ijo.2015.3139

Ejemplares similares