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Delivery of DNAzyme targeting aurora kinase A to inhibit the proliferation and migration of human prostate cancer

Herein, a polyethylenimine derivative N-acetyl-l-leucine-polyethylenimine (N-Ac-l-Leu-PEI) was employed as a carrier to achieve the delivery of DNAzyme targeting aurora kinase A using PC-3 cell as a model. Flow cytometry and confocal laser scanning microscopy demonstrated that the derivative could r...

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Detalles Bibliográficos
Autores principales: Xing, Zhen, Gao, Sai, Duan, Yan, Han, Haobo, Li, Li, Yang, Yan, Li, Quanshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583550/
https://www.ncbi.nlm.nih.gov/pubmed/26425080
http://dx.doi.org/10.2147/IJN.S90559