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Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia

Schizophrenia (SZ) is a severe chronic psychiatric disorder with wide prevalence and high morbidity. We know little about SZ's etiology and pathophysiology at present. The study of gene expression profile is useful for us to identify potential biomarkers at molecular level and explain possible...

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Detalles Bibliográficos
Autores principales: Sun, Li, Cheng, Zaohuo, Zhang, Fuquan, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583616/
https://www.ncbi.nlm.nih.gov/pubmed/26484249
http://dx.doi.org/10.1016/j.gdata.2015.04.022
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author Sun, Li
Cheng, Zaohuo
Zhang, Fuquan
Xu, Yong
author_facet Sun, Li
Cheng, Zaohuo
Zhang, Fuquan
Xu, Yong
author_sort Sun, Li
collection PubMed
description Schizophrenia (SZ) is a severe chronic psychiatric disorder with wide prevalence and high morbidity. We know little about SZ's etiology and pathophysiology at present. The study of gene expression profile is useful for us to identify potential biomarkers at molecular level and explain possible pathogenesis of SZ. Therefore we recently compared gene expression profiles in PMBCs from EOS cases and healthy controls using microarrays. Here we will describe in detail the contents and quality control of the microarray experiment. The raw microarray data are accessible through GEO series accession number GSE54913.
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spelling pubmed-45836162015-10-19 Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia Sun, Li Cheng, Zaohuo Zhang, Fuquan Xu, Yong Genom Data Data in Brief Schizophrenia (SZ) is a severe chronic psychiatric disorder with wide prevalence and high morbidity. We know little about SZ's etiology and pathophysiology at present. The study of gene expression profile is useful for us to identify potential biomarkers at molecular level and explain possible pathogenesis of SZ. Therefore we recently compared gene expression profiles in PMBCs from EOS cases and healthy controls using microarrays. Here we will describe in detail the contents and quality control of the microarray experiment. The raw microarray data are accessible through GEO series accession number GSE54913. Elsevier 2015-06-09 /pmc/articles/PMC4583616/ /pubmed/26484249 http://dx.doi.org/10.1016/j.gdata.2015.04.022 Text en © 2015 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Data in Brief
Sun, Li
Cheng, Zaohuo
Zhang, Fuquan
Xu, Yong
Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia
title Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia
title_full Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia
title_fullStr Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia
title_full_unstemmed Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia
title_short Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia
title_sort gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia
topic Data in Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583616/
https://www.ncbi.nlm.nih.gov/pubmed/26484249
http://dx.doi.org/10.1016/j.gdata.2015.04.022
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