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Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia
Schizophrenia (SZ) is a severe chronic psychiatric disorder with wide prevalence and high morbidity. We know little about SZ's etiology and pathophysiology at present. The study of gene expression profile is useful for us to identify potential biomarkers at molecular level and explain possible...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583616/ https://www.ncbi.nlm.nih.gov/pubmed/26484249 http://dx.doi.org/10.1016/j.gdata.2015.04.022 |
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author | Sun, Li Cheng, Zaohuo Zhang, Fuquan Xu, Yong |
author_facet | Sun, Li Cheng, Zaohuo Zhang, Fuquan Xu, Yong |
author_sort | Sun, Li |
collection | PubMed |
description | Schizophrenia (SZ) is a severe chronic psychiatric disorder with wide prevalence and high morbidity. We know little about SZ's etiology and pathophysiology at present. The study of gene expression profile is useful for us to identify potential biomarkers at molecular level and explain possible pathogenesis of SZ. Therefore we recently compared gene expression profiles in PMBCs from EOS cases and healthy controls using microarrays. Here we will describe in detail the contents and quality control of the microarray experiment. The raw microarray data are accessible through GEO series accession number GSE54913. |
format | Online Article Text |
id | pubmed-4583616 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-45836162015-10-19 Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia Sun, Li Cheng, Zaohuo Zhang, Fuquan Xu, Yong Genom Data Data in Brief Schizophrenia (SZ) is a severe chronic psychiatric disorder with wide prevalence and high morbidity. We know little about SZ's etiology and pathophysiology at present. The study of gene expression profile is useful for us to identify potential biomarkers at molecular level and explain possible pathogenesis of SZ. Therefore we recently compared gene expression profiles in PMBCs from EOS cases and healthy controls using microarrays. Here we will describe in detail the contents and quality control of the microarray experiment. The raw microarray data are accessible through GEO series accession number GSE54913. Elsevier 2015-06-09 /pmc/articles/PMC4583616/ /pubmed/26484249 http://dx.doi.org/10.1016/j.gdata.2015.04.022 Text en © 2015 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Data in Brief Sun, Li Cheng, Zaohuo Zhang, Fuquan Xu, Yong Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia |
title | Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia |
title_full | Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia |
title_fullStr | Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia |
title_full_unstemmed | Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia |
title_short | Gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia |
title_sort | gene expression profiling in peripheral blood mononuclear cells of early-onset schizophrenia |
topic | Data in Brief |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583616/ https://www.ncbi.nlm.nih.gov/pubmed/26484249 http://dx.doi.org/10.1016/j.gdata.2015.04.022 |
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