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A destructive feedback loop mediated by CXCL10 in central nervous system inflammatory disease

OBJECTIVE: Paraneoplastic neurologic disorders (PND) are autoimmune diseases associated with cancer and ectopic expression of a neuronal antigen in a peripheral tumor. Patients with PND harbor high‐titer antibodies and T cells in their serum and cerebrospinal fluid (CSF) that are specific to the tum...

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Detalles Bibliográficos
Autores principales: Roberts, Wendy K., Blachère, Nathalie E., Frank, Mayu O., Dousmanis, Athanasios, Ransohoff, Richard M., Darnell, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583819/
https://www.ncbi.nlm.nih.gov/pubmed/26224283
http://dx.doi.org/10.1002/ana.24494