Novel targeted siRNA-loaded hybrid nanoparticles: preparation, characterization and in vitro evaluation

BACKGROUND: siRNAs have a high potential for silencing critical molecular pathways that are pathogenic. Nevertheless, their clinical application has been limited by a lack of effective and safe nanotechnology-based delivery system that allows a controlled and safe transfection to cytosol of targeted...

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Detalles Bibliográficos
Autores principales: Dim, Nneka, Perepelyuk, Maryna, Gomes, Olukayode, Thangavel, Chellappagounder, Liu, Yi, Den, Robert, Lakshmikuttyamma, Ashakumary, Shoyele, Sunday A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583992/
https://www.ncbi.nlm.nih.gov/pubmed/26410728
http://dx.doi.org/10.1186/s12951-015-0124-2

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