Cargando…

Markers of Collagen Remodeling Detect Clinically Significant Fibrosis in Chronic Hepatitis C Patients

BACKGROUND AND AIM: Detection of advanced fibrosis (Metavir F≥3) is important to identify patients with a high urgency of antiviral treatments vs. those whose treatment could be deferred (F≤2). The aim was to assess the diagnostic value of novel serological extracellular matrix protein fragments as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nielsen, Mette J., Kazankov, Konstantin, Leeming, Diana J., Karsdal, Morten A., Krag, Aleksander, Barrera, Francisco, McLeod, Duncan, George, Jacob, Grønbæk, Henning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583995/ https://www.ncbi.nlm.nih.gov/pubmed/26406331 http://dx.doi.org/10.1371/journal.pone.0137302

Ejemplares similares

Progressive alcohol‐related liver fibrosis is characterised by imbalanced collagen formation and degradation
por: Thiele, Maja, et al.
Publicado: (2021)

Collagen type IV remodelling gender‐specifically predicts mortality in decompensated cirrhosis
por: Lehmann, Jennifer, et al.
Publicado: (2019)

Serum markers of the extracellular matrix remodeling reflect antifibrotic therapy in bile-duct ligated rats
por: Schierwagen, Robert, et al.
Publicado: (2013)

Phosphodiesterase inhibition mediates matrix metalloproteinase activity and the level of collagen degradation fragments in a liver fibrosis ex vivo rat model
por: Veidal, Sanne Skovgård, et al.
Publicado: (2012)

Serum markers of type III and IV procollagen processing predict recurrence of fibrosis in liver transplanted patients
por: Nielsen, Mette Juul, et al.
Publicado: (2019)

Quantification of extracellular matrix remodeling for the non-invasive identification of graft fibrosis after liver transplantation
por: Engel, Bastian, et al.
Publicado: (2023)

PRO‐C3 and ADAPT algorithm accurately identify patients with advanced fibrosis due to alcohol‐related liver disease
por: Madsen, Bjørn S., et al.
Publicado: (2021)

No effect of rifaximin on soluble CD163, mannose receptor or type III and IV neoepitope collagen markers in decompensated cirrhosis: Results from a randomized, placebo controlled trial
por: Kimer, Nina, et al.
Publicado: (2018)

Acute decompensation boosts hepatic collagen type III deposition and deteriorates experimental and human cirrhosis
por: Praktiknjo, Michael, et al.
Publicado: (2018)

Serological Investigation of the Collagen Degradation Profile of Patients with Chronic Obstructive Pulmonary Disease or Idiopathic Pulmonary Fibrosis
por: Leeming, Diana J., et al.
Publicado: (2012)

Endotrophin and C6Ma3, serological biomarkers of type VI collagen remodelling, reflect endoscopic and clinical disease activity in IBD
por: Lindholm, Majken, et al.
Publicado: (2021)

Macrophage Activation Markers, Soluble CD163 and Mannose Receptor, in Liver Fibrosis
por: Gantzel, Rasmus Hvidbjerg, et al.
Publicado: (2021)

Liver-related effects of chronic hepatitis C antiviral treatment
por: Laursen, Tea L, et al.
Publicado: (2020)

Circulating levels of endotrophin and cross-linked type III collagen reflect liver fibrosis in people with HIV
por: Dold, Leona, et al.
Publicado: (2023)

MMP Mediated Degradation of Type IV Collagen Alpha 1 and Alpha 3 Chains Reflects Basement Membrane Remodeling in Experimental and Clinical Fibrosis – Validation of Two Novel Biomarker Assays
por: Sand, Jannie Marie, et al.
Publicado: (2013)

Serum Type XIX Collagen is Significantly Elevated in Non-Small Cell Lung Cancer: A Preliminary Study on Biomarker Potential
por: Thorlacius-Ussing, Jeppe, et al.
Publicado: (2020)

An MMP‐degraded and cross‐linked fragment of type III collagen as a non‐invasive biomarker of hepatic fibrosis resolution
por: Pehrsson, Martin, et al.
Publicado: (2022)

High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD – results from the ECLIPSE study
por: Sand, Jannie M. B., et al.
Publicado: (2016)

Molecular Serum Markers of Liver Fibrosis
por: Liu, Tianhui, et al.
Publicado: (2012)

Endotrophin, a pro-peptide of Type VI collagen, is a biomarker of survival in cirrhotic patients with hepatocellular carcinoma
por: Leeming, Diana Julie, et al.
Publicado: (2020)

Association of Systemic Collagen Type IV Formation with Survival among Patients Undergoing Hemodialysis
por: Leeming, Diana J., et al.
Publicado: (2013)

Macrophage Markers Do Not Add to the Prediction of Liver Fibrosis by Transient Elastography in Patients With Metabolic Associated Fatty Liver Disease
por: Kazankov, Konstantin, et al.
Publicado: (2020)

Assessment of proteolytic degradation of the basement membrane: a fragment of type IV collagen as a biochemical marker for liver fibrosis
por: Veidal, Sanne S, et al.
Publicado: (2011)

LPA(1) antagonist BMS-986020 changes collagen dynamics and exerts antifibrotic effects in vitro and in patients with idiopathic pulmonary fibrosis
por: Decato, Benjamin E., et al.
Publicado: (2022)

Cross-Linked Multimeric Pro-Peptides of Type III Collagen (PC3X) in Hepatocellular Carcinoma – A Biomarker That Provides Additional Prognostic Value in AFP Positive Patients
por: Jensen, Christina, et al.
Publicado: (2020)

Macrophage activation marker sCD163 is associated with liver injury and hepatic insulin resistance in obese patients before and after Roux‐en‐Y gastric bypass
por: Kazankov, Konstantin, et al.
Publicado: (2022)

Circulating Levels of a Collagen Type V Propeptide Fragment in a Carbon Tetrachloride Reversible Model of Liver Fibrosis
por: Vassiliadis, E., et al.
Publicado: (2012)

The extracellular matrix in the kidney: a source of novel non-invasive biomarkers of kidney fibrosis?
por: Genovese, Federica, et al.
Publicado: (2014)

Longitudinal serological assessment of type VI collagen turnover is related to progression in a real-world cohort of idiopathic pulmonary fibrosis
por: Jessen, Henrik, et al.
Publicado: (2021)

Markers of Basement Membrane Remodeling Are Associated With Higher Mortality in Patients With Known Atherosclerosis
por: Holm Nielsen, Signe, et al.
Publicado: (2018)

Serological assessment of neutrophil elastase activity on elastin during lung ECM remodeling
por: Kristensen, Jacob H, et al.
Publicado: (2015)

Precision-Cut Kidney Slices as a Tool to Understand the Dynamics of Extracellular Matrix Remodeling in Renal Fibrosis
por: Genovese, Federica, et al.
Publicado: (2016)

Serum type XVI collagen is associated with colorectal cancer and ulcerative colitis indicating a pathological role in gastrointestinal disorders
por: Jensen, Christina, et al.
Publicado: (2018)

Turnover of type I and III collagen predicts progression of idiopathic pulmonary fibrosis
por: Jessen, H., et al.
Publicado: (2021)

MMP Mediated Degradation of Type VI Collagen Is Highly Associated with Liver Fibrosis – Identification and Validation of a Novel Biochemical Marker Assay
por: Veidal, Sanne Skovgård, et al.
Publicado: (2011)

PRO-C3-Levels in Patients with HIV/HCV-Co-Infection Reflect Fibrosis Stage and Degree of Portal Hypertension
por: Jansen, Christian, et al.
Publicado: (2014)

Measurement of matrix metalloproteinase 9-mediated Collagen type III degradation fragment as a marker of skin fibrosis
por: Vassiliadis, Efstathios, et al.
Publicado: (2011)

PRO‐C3, a Serological Marker of Fibrosis, During Childhood and Correlations With Fibrosis in Pediatric NAFLD
por: Cohen, Catherine C., et al.
Publicado: (2021)

Tissue turnover of collagen type I, III and elastin is elevated in the PCLS model of IPF and can be restored back to vehicle levels using a phosphodiesterase inhibitor
por: Hansen, Niels Ulrik Brandt, et al.
Publicado: (2016)

Nintedanib modulates type III collagen turnover in viable precision-cut lung slices from bleomycin-treated rats and patients with pulmonary fibrosis
por: Hesse, Christina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_c0l4llkb1ru4o8koiif095as68