miRNAs modified by dietary lipids in Caco-2 cells. A microarray screening

We performed a screening of miRNAs regulated by dietary lipids in a cellular model of enterocytes, Caco-2 cells. Our aim was to describe new lipid-modified miRNAs with an implication in lipid homeostasis and cardiovascular disease [1], [2]. For that purpose, we treated differentiated Caco-2 cells wi...

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Detalles Bibliográficos
Autores principales: Daimiel, Lidia, Ordovás, Jose Mª., Dávalos, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Data in Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584012/
https://www.ncbi.nlm.nih.gov/pubmed/26484250
http://dx.doi.org/10.1016/j.gdata.2015.05.011
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author Daimiel, Lidia
Ordovás, Jose Mª.
Dávalos, Alberto
author_facet Daimiel, Lidia
Ordovás, Jose Mª.
Dávalos, Alberto
author_sort Daimiel, Lidia
collection PubMed
description We performed a screening of miRNAs regulated by dietary lipids in a cellular model of enterocytes, Caco-2 cells. Our aim was to describe new lipid-modified miRNAs with an implication in lipid homeostasis and cardiovascular disease [1], [2]. For that purpose, we treated differentiated Caco-2 cells with micelles containing the assayed lipids (cholesterol, conjugated linoleic acid and docosahexaenoic acid) and the screening of miRNAs was carried out by microarray using the μParaflo®Microfluidic Biochip Technology of LC Sciences (Huston, TX, USA). Experimental design, microarray description and raw data have been made available in the GEO database with the reference number of GSE59153. Here we described in detail the experimental design and methods used to obtain the relative expression data.
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spelling pubmed-45840122015-10-19 miRNAs modified by dietary lipids in Caco-2 cells. A microarray screening Daimiel, Lidia Ordovás, Jose Mª. Dávalos, Alberto Genom Data Data in Brief We performed a screening of miRNAs regulated by dietary lipids in a cellular model of enterocytes, Caco-2 cells. Our aim was to describe new lipid-modified miRNAs with an implication in lipid homeostasis and cardiovascular disease [1], [2]. For that purpose, we treated differentiated Caco-2 cells with micelles containing the assayed lipids (cholesterol, conjugated linoleic acid and docosahexaenoic acid) and the screening of miRNAs was carried out by microarray using the μParaflo®Microfluidic Biochip Technology of LC Sciences (Huston, TX, USA). Experimental design, microarray description and raw data have been made available in the GEO database with the reference number of GSE59153. Here we described in detail the experimental design and methods used to obtain the relative expression data. Elsevier 2015-06-09 /pmc/articles/PMC4584012/ /pubmed/26484250 http://dx.doi.org/10.1016/j.gdata.2015.05.011 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Data in Brief
Daimiel, Lidia
Ordovás, Jose Mª.
Dávalos, Alberto
miRNAs modified by dietary lipids in Caco-2 cells. A microarray screening
title miRNAs modified by dietary lipids in Caco-2 cells. A microarray screening
title_full miRNAs modified by dietary lipids in Caco-2 cells. A microarray screening
title_fullStr miRNAs modified by dietary lipids in Caco-2 cells. A microarray screening
title_full_unstemmed miRNAs modified by dietary lipids in Caco-2 cells. A microarray screening
title_short miRNAs modified by dietary lipids in Caco-2 cells. A microarray screening
title_sort mirnas modified by dietary lipids in caco-2 cells. a microarray screening
topic Data in Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584012/
https://www.ncbi.nlm.nih.gov/pubmed/26484250
http://dx.doi.org/10.1016/j.gdata.2015.05.011
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