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Modulation of Spinal GABAergic Inhibition and Mechanical Hypersensitivity following Chronic Compression of Dorsal Root Ganglion in the Rat

Chronic compression of dorsal root ganglion (CCD) results in neuropathic pain. We investigated the role of spinal GABA in CCD-induced pain using rats with unilateral CCD. A stereological analysis revealed that the proportion of GABA-immunoreactive neurons to total neurons at L4/5 laminae I–III on th...

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Detalles Bibliográficos
Autores principales: Lee, Moon Chul, Nam, Taick Sang, Jung, Se Jung, Gwak, Young S., Leem, Joong Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584224/
https://www.ncbi.nlm.nih.gov/pubmed/26451259
http://dx.doi.org/10.1155/2015/924728