Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily

Poxviruses encode a broad array of proteins that serve to undermine host immune defenses. Structural analysis of four of these seemingly unrelated proteins revealed the recurrent use of a conserved beta-sandwich fold that has not been observed in any eukaryotic or prokaryotic protein. Herein we prop...

Descripción completa

Detalles Bibliográficos
Autores principales: Nelson, Christopher A., Epperson, Megan L., Singh, Sukrit, Elliott, Jabari I., Fremont, Daved H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584292/
https://www.ncbi.nlm.nih.gov/pubmed/26343707
http://dx.doi.org/10.3390/v7092848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584292/
https://www.ncbi.nlm.nih.gov/pubmed/26343707
http://dx.doi.org/10.3390/v7092848

Ejemplares similares