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The Fyn–ADAP Axis: Cytotoxicity Versus Cytokine Production in Killer Cells
Lymphocyte signaling cascades responsible for anti-tumor cytotoxicity and inflammatory cytokine production must be tightly regulated in order to control an immune response. Disruption of these cascades can cause immune suppression as seen in a tumor microenvironment, and loss of signaling integrity...
Autores principales: | Gerbec, Zachary J., Thakar, Monica S., Malarkannan, Subramaniam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584950/ https://www.ncbi.nlm.nih.gov/pubmed/26441977 http://dx.doi.org/10.3389/fimmu.2015.00472 |
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