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The Fyn–ADAP Axis: Cytotoxicity Versus Cytokine Production in Killer Cells

Lymphocyte signaling cascades responsible for anti-tumor cytotoxicity and inflammatory cytokine production must be tightly regulated in order to control an immune response. Disruption of these cascades can cause immune suppression as seen in a tumor microenvironment, and loss of signaling integrity...

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Detalles Bibliográficos
Autores principales: Gerbec, Zachary J., Thakar, Monica S., Malarkannan, Subramaniam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584950/
https://www.ncbi.nlm.nih.gov/pubmed/26441977
http://dx.doi.org/10.3389/fimmu.2015.00472

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