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Fragmentation and Coverage Variation in Viral Metagenome Assemblies, and Their Effect in Diversity Calculations

Metagenomic libraries consist of DNA fragments from diverse species, with varying genome size and abundance. High-throughput sequencing platforms produce large volumes of reads from these libraries, which may be assembled into contigs, ideally resembling the original larger genomic sequences. The un...

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Detalles Bibliográficos
Autores principales: García-López, Rodrigo, Vázquez-Castellanos, Jorge Francisco, Moya, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585024/
https://www.ncbi.nlm.nih.gov/pubmed/26442255
http://dx.doi.org/10.3389/fbioe.2015.00141