Inhibition of Immune Checkpoints and Vascular Endothelial Growth Factor as Combination Therapy for Metastatic Melanoma: An Overview of Rationale, Preclinical Evidence, and Initial Clinical Data

The role of angiogenesis as a mediator of immune regulation in the tumor microenvironment has recently come into focus. Furthermore, emerging evidence indicates that immunotherapy can lead to immune-mediated vasculopathy in the tumor, suggesting that the tumor vasculature may be an important interfa...

Descripción completa

Detalles Bibliográficos
Autores principales: Ott, Patrick A., Hodi, F. Stephen, Buchbinder, Elizabeth I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585112/
https://www.ncbi.nlm.nih.gov/pubmed/26442214
http://dx.doi.org/10.3389/fonc.2015.00202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585112/
https://www.ncbi.nlm.nih.gov/pubmed/26442214
http://dx.doi.org/10.3389/fonc.2015.00202

Ejemplares similares