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Functional characterization of ivermectin binding sites in α1β2γ2L GABA(A) receptors

GABA(A) receptors (GABA(A)Rs) are the major inhibitory neurotransmitter receptors in the brain and are therapeutic targets for many indications including sedation, anesthesia and anxiolysis. There is, however, considerable scope for the development of new therapeutics with improved beneficial effect...

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Detalles Bibliográficos
Autores principales: Estrada-Mondragon, Argel, Lynch, Joseph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585179/
https://www.ncbi.nlm.nih.gov/pubmed/26441518
http://dx.doi.org/10.3389/fnmol.2015.00055