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Differences in Signal Activation by LH and hCG are Mediated by the LH/CG Receptor’s Extracellular Hinge Region
The human lutropin (hLH)/choriogonadotropin (hCG) receptor (LHCGR) can be activated by binding two slightly different gonadotropic glycoprotein hormones, choriogonadotropin (CG) – secreted by the placenta, and lutropin (LH) – produced by the pituitary. They induce different signaling profiles at the...
Autores principales: | Grzesik, Paul, Kreuchwig, Annika, Rutz, Claudia, Furkert, Jens, Wiesner, Burkhard, Schuelein, Ralf, Kleinau, Gunnar, Gromoll, Joerg, Krause, Gerd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585211/ https://www.ncbi.nlm.nih.gov/pubmed/26441830 http://dx.doi.org/10.3389/fendo.2015.00140 |
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