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Fusion and Fission of Cognitive Functions in the Human Parietal Cortex

How is higher cognitive function organized in the human parietal cortex? A century of neuropsychology and 30 years of functional neuroimaging has implicated the parietal lobe in many different verbal and nonverbal cognitive domains. There is little clarity, however, on how these functions are organi...

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Autores principales: Humphreys, Gina F., Lambon Ralph, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585503/
https://www.ncbi.nlm.nih.gov/pubmed/25205661
http://dx.doi.org/10.1093/cercor/bhu198
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author Humphreys, Gina F.
Lambon Ralph, Matthew A.
author_facet Humphreys, Gina F.
Lambon Ralph, Matthew A.
author_sort Humphreys, Gina F.
collection PubMed
description How is higher cognitive function organized in the human parietal cortex? A century of neuropsychology and 30 years of functional neuroimaging has implicated the parietal lobe in many different verbal and nonverbal cognitive domains. There is little clarity, however, on how these functions are organized, that is, where do these functions coalesce (implying a shared, underpinning neurocomputation) and where do they divide (indicating different underlying neural functions). Until now, there has been no multi-domain synthesis in order to reveal where there is fusion or fission of functions in the parietal cortex. This aim was achieved through a large-scale activation likelihood estimation (ALE) analysis of 386 studies (3952 activation peaks) covering 8 cognitive domains. A tripartite, domain-general neuroanatomical division and 5 principles of cognitive organization were established, and these are discussed with respect to a unified theory of parietal functional organization.
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spelling pubmed-45855032015-09-29 Fusion and Fission of Cognitive Functions in the Human Parietal Cortex Humphreys, Gina F. Lambon Ralph, Matthew A. Cereb Cortex Articles How is higher cognitive function organized in the human parietal cortex? A century of neuropsychology and 30 years of functional neuroimaging has implicated the parietal lobe in many different verbal and nonverbal cognitive domains. There is little clarity, however, on how these functions are organized, that is, where do these functions coalesce (implying a shared, underpinning neurocomputation) and where do they divide (indicating different underlying neural functions). Until now, there has been no multi-domain synthesis in order to reveal where there is fusion or fission of functions in the parietal cortex. This aim was achieved through a large-scale activation likelihood estimation (ALE) analysis of 386 studies (3952 activation peaks) covering 8 cognitive domains. A tripartite, domain-general neuroanatomical division and 5 principles of cognitive organization were established, and these are discussed with respect to a unified theory of parietal functional organization. Oxford University Press 2015-10 2014-09-09 /pmc/articles/PMC4585503/ /pubmed/25205661 http://dx.doi.org/10.1093/cercor/bhu198 Text en © The Author 2014. Published by Oxford University Press http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Humphreys, Gina F.
Lambon Ralph, Matthew A.
Fusion and Fission of Cognitive Functions in the Human Parietal Cortex
title Fusion and Fission of Cognitive Functions in the Human Parietal Cortex
title_full Fusion and Fission of Cognitive Functions in the Human Parietal Cortex
title_fullStr Fusion and Fission of Cognitive Functions in the Human Parietal Cortex
title_full_unstemmed Fusion and Fission of Cognitive Functions in the Human Parietal Cortex
title_short Fusion and Fission of Cognitive Functions in the Human Parietal Cortex
title_sort fusion and fission of cognitive functions in the human parietal cortex
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585503/
https://www.ncbi.nlm.nih.gov/pubmed/25205661
http://dx.doi.org/10.1093/cercor/bhu198
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