Structural basis for the inhibition of voltage-dependent K(+) channel by gating modifier toxin

Voltage-dependent K(+) (K(v)) channels play crucial roles in nerve and muscle action potentials. Voltage-sensing domains (VSDs) of K(v) channels sense changes in the transmembrane potential, regulating the K(+)-permeability across the membrane. Gating modifier toxins, which have been used for the fu...

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Detalles Bibliográficos
Autores principales: Ozawa, Shin-ichiro, Kimura, Tomomi, Nozaki, Tomohiro, Harada, Hitomi, Shimada, Ichio, Osawa, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585561/
https://www.ncbi.nlm.nih.gov/pubmed/26382304
http://dx.doi.org/10.1038/srep14226

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