LINGO-1 antibody ameliorates myelin impairment and spatial memory deficits in experimental autoimmune encephalomyelitis mice

More than 50% of multiple sclerosis patients develop cognitive impairment. However, the underlying mechanisms are still unclear, and there is no effective treatment. LINGO-1 (LRR and Ig domain containing NOGO receptor interacting protein 1) has been identified as an inhibitor of oligodendrocyte diff...

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Detalles Bibliográficos
Autores principales: Sun, Jun-Jun, Ren, Qing-Guo, Xu, Lin, Zhang, Zhi-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585639/
https://www.ncbi.nlm.nih.gov/pubmed/26383267
http://dx.doi.org/10.1038/srep14235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585639/
https://www.ncbi.nlm.nih.gov/pubmed/26383267
http://dx.doi.org/10.1038/srep14235

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