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A new minimally-invasive method for microinjection into the mouse spinal dorsal horn

Noninvasive gene delivery to the spinal dorsal horn (SDH) remains challenging because existing methods to directly microinject vectors require laminectomy, which leads to tissue damage and inflammation. Such responses might hamper accurate readouts of cellular and behavioural effects of an introduce...

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Detalles Bibliográficos
Autores principales: Kohro, Yuta, Sakaguchi, Emi, Tashima, Ryoichi, Tozaki-Saitoh, Hidetoshi, Okano, Hideyuki, Inoue, Kazuhide, Tsuda, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585681/
https://www.ncbi.nlm.nih.gov/pubmed/26387932
http://dx.doi.org/10.1038/srep14306