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A new minimally-invasive method for microinjection into the mouse spinal dorsal horn
Noninvasive gene delivery to the spinal dorsal horn (SDH) remains challenging because existing methods to directly microinject vectors require laminectomy, which leads to tissue damage and inflammation. Such responses might hamper accurate readouts of cellular and behavioural effects of an introduce...
Autores principales: | Kohro, Yuta, Sakaguchi, Emi, Tashima, Ryoichi, Tozaki-Saitoh, Hidetoshi, Okano, Hideyuki, Inoue, Kazuhide, Tsuda, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585681/ https://www.ncbi.nlm.nih.gov/pubmed/26387932 http://dx.doi.org/10.1038/srep14306 |
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