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Lessons in Protein Design from Combined Evolution and Conformational Dynamics

Protein-protein interactions play important roles in the control of every cellular process. How natural selection has optimized protein design to produce molecules capable of binding to many partner proteins is a fascinating problem but not well understood. Here, we performed a combinatorial analysi...

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Detalles Bibliográficos
Autores principales: Tripathi, Swarnendu, Waxham, M. Neal, Cheung, Margaret S., Liu, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585694/
https://www.ncbi.nlm.nih.gov/pubmed/26388515
http://dx.doi.org/10.1038/srep14259

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