REG4 is a transcriptional target of GATA6 and is essential for colorectal tumorigenesis

The transcription factor GATA6 is a critical regulator of cell proliferation and development in the gastrointestinal tract. We have recently reported that GATA6 induces the expression of the intestinal stem cell marker LGR5 and enhances the clonogenicity and tumorigenicity of colon cancer cells, but...

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Detalles Bibliográficos
Autores principales: Kawasaki, Yoshihiro, Matsumura, Kosuke, Miyamoto, Masaya, Tsuji, Shinnosuke, Okuno, Masumi, Suda, Sakiko, Hiyoshi, Masaya, Kitayama, Joji, Akiyama, Tetsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585703/
https://www.ncbi.nlm.nih.gov/pubmed/26387746
http://dx.doi.org/10.1038/srep14291

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