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Calreticulin is required for development of the cumulus oocyte complex and female fertility

Calnexin (CANX) and calreticulin (CALR) chaperones mediate nascent glycoprotein folding in the endoplasmic reticulum. Here we report that these chaperones have distinct roles in male and female fertility. Canx null mice are growth retarded but fertile. Calr null mice die during embryonic development...

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Detalles Bibliográficos
Autores principales:	Tokuhiro, Keizo, Satouh, Yuhkoh, Nozawa, Kaori, Isotani, Ayako, Fujihara, Yoshitaka, Hirashima, Yumiko, Matsumura, Hiroyuki, Takumi, Kazuhiro, Miyano, Takashi, Okabe, Masaru, Benham, Adam M., Ikawa, Masahito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585710/ https://www.ncbi.nlm.nih.gov/pubmed/26388295 http://dx.doi.org/10.1038/srep14254

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