Lack of association of the iNOS gene polymorphism with risk of cancer: a systematic review and Meta-Analysis

In order to investigate the association between the iNOS gene polymorphisms and susceptibility to cancer, a search of English papers was done using Pubmed, the Cochrane Library, Embase, ISI Web of Science, Google (scholar) database, and all Chinese reports were conducted using CBMDisc, Chongqing VIP...

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Detalles Bibliográficos
Autores principales: Jiao, Jinghua, Wu, Jingyang, Huang, Desheng, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585729/
https://www.ncbi.nlm.nih.gov/pubmed/26391304
http://dx.doi.org/10.1038/srep09889
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author Jiao, Jinghua
Wu, Jingyang
Huang, Desheng
Liu, Lei
author_facet Jiao, Jinghua
Wu, Jingyang
Huang, Desheng
Liu, Lei
author_sort Jiao, Jinghua
collection PubMed
description In order to investigate the association between the iNOS gene polymorphisms and susceptibility to cancer, a search of English papers was done using Pubmed, the Cochrane Library, Embase, ISI Web of Science, Google (scholar) database, and all Chinese reports were conducted using CBMDisc, Chongqing VIP database, and CNKI database. A total of eight studies were included in this meta-analysis including 1,920 cases and 2,373 controls. The results indicated that the polymorphisms in iNOS gene (C150T(Ser(608) Leu) polymorphism and polymorphic (CCTTT)n repeats) had no association with cancer risk for all genetic models. This meta-analysis suggested that the polymorphisms in the iNOS gene were not associated with cancer risk.
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spelling pubmed-45857292015-09-29 Lack of association of the iNOS gene polymorphism with risk of cancer: a systematic review and Meta-Analysis Jiao, Jinghua Wu, Jingyang Huang, Desheng Liu, Lei Sci Rep Article In order to investigate the association between the iNOS gene polymorphisms and susceptibility to cancer, a search of English papers was done using Pubmed, the Cochrane Library, Embase, ISI Web of Science, Google (scholar) database, and all Chinese reports were conducted using CBMDisc, Chongqing VIP database, and CNKI database. A total of eight studies were included in this meta-analysis including 1,920 cases and 2,373 controls. The results indicated that the polymorphisms in iNOS gene (C150T(Ser(608) Leu) polymorphism and polymorphic (CCTTT)n repeats) had no association with cancer risk for all genetic models. This meta-analysis suggested that the polymorphisms in the iNOS gene were not associated with cancer risk. Nature Publishing Group 2015-09-22 /pmc/articles/PMC4585729/ /pubmed/26391304 http://dx.doi.org/10.1038/srep09889 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Jiao, Jinghua
Wu, Jingyang
Huang, Desheng
Liu, Lei
Lack of association of the iNOS gene polymorphism with risk of cancer: a systematic review and Meta-Analysis
title Lack of association of the iNOS gene polymorphism with risk of cancer: a systematic review and Meta-Analysis
title_full Lack of association of the iNOS gene polymorphism with risk of cancer: a systematic review and Meta-Analysis
title_fullStr Lack of association of the iNOS gene polymorphism with risk of cancer: a systematic review and Meta-Analysis
title_full_unstemmed Lack of association of the iNOS gene polymorphism with risk of cancer: a systematic review and Meta-Analysis
title_short Lack of association of the iNOS gene polymorphism with risk of cancer: a systematic review and Meta-Analysis
title_sort lack of association of the inos gene polymorphism with risk of cancer: a systematic review and meta-analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585729/
https://www.ncbi.nlm.nih.gov/pubmed/26391304
http://dx.doi.org/10.1038/srep09889
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AT huangdesheng lackofassociationoftheinosgenepolymorphismwithriskofcancerasystematicreviewandmetaanalysis
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