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Edges of human embryonic stem cell colonies display distinct mechanical properties and differentiation potential

In order to understand the mechanisms that guide cell fate decisions during early human development, we closely examined the differentiation process in adherent colonies of human embryonic stem cells (hESCs). Live imaging of the differentiation process reveals that cells on the outer edge of the und...

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Detalles Bibliográficos
Autores principales:	Rosowski, Kathryn A., Mertz, Aaron F., Norcross, Samuel, Dufresne, Eric R., Horsley, Valerie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585749/ https://www.ncbi.nlm.nih.gov/pubmed/26391588 http://dx.doi.org/10.1038/srep14218

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