In vitro discovery of promising anti-cancer drug combinations using iterative maximisation of a therapeutic index

In vitro-based search for promising anti-cancer drug combinations may provide important leads to improved cancer therapies. Currently there are no integrated computational-experimental methods specifically designed to search for combinations, maximizing a predefined therapeutic index (TI) defined in...

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Detalles Bibliográficos
Autores principales: Kashif, M., Andersson, C., Hassan, S., Karlsson, H., Senkowski, W., Fryknäs, M., Nygren, P., Larsson, R., Gustafsson, M.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585751/
https://www.ncbi.nlm.nih.gov/pubmed/26392291
http://dx.doi.org/10.1038/srep14118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585751/
https://www.ncbi.nlm.nih.gov/pubmed/26392291
http://dx.doi.org/10.1038/srep14118

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