A novel microtubule de-stabilizing complementarity-determining region C36L1 peptide displays antitumor activity against melanoma in vitro and in vivo

Short peptide sequences from complementarity-determining regions (CDRs) of different immunoglobulins may exert anti-infective, immunomodulatory and antitumor activities regardless of the specificity of the original monoclonal antibody (mAb). In this sense, they resemble early molecules of innate imm...

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Detalles Bibliográficos
Autores principales: Figueiredo, Carlos R., Matsuo, Alisson L., Azevedo, Ricardo A., Massaoka, Mariana H., Girola, Natalia, Polonelli, Luciano, Travassos, Luiz R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585759/
https://www.ncbi.nlm.nih.gov/pubmed/26391685
http://dx.doi.org/10.1038/srep14310

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