A Molecular Toolkit to Visualize Native Protein Assemblies in the Context of Human Disease

We present a new molecular toolkit to investigate protein assemblies natively formed in the context of human disease. The system employs tunable microchips that can be decorated with switchable adaptor molecules to select for target proteins of interest and analyze them using molecular microscopy. I...

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Detalles Bibliográficos
Autores principales: Gilmore, Brian L., Winton, Carly E., Demmert, Andrew C., Tanner, Justin R., Bowman, Sam, Karageorge, Vasilea, Patel, Kaya, Sheng, Zhi, Kelly, Deborah F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585766/
https://www.ncbi.nlm.nih.gov/pubmed/26395823
http://dx.doi.org/10.1038/srep14440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585766/
https://www.ncbi.nlm.nih.gov/pubmed/26395823
http://dx.doi.org/10.1038/srep14440

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