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A Molecular Toolkit to Visualize Native Protein Assemblies in the Context of Human Disease
We present a new molecular toolkit to investigate protein assemblies natively formed in the context of human disease. The system employs tunable microchips that can be decorated with switchable adaptor molecules to select for target proteins of interest and analyze them using molecular microscopy. I...
Autores principales: | Gilmore, Brian L., Winton, Carly E., Demmert, Andrew C., Tanner, Justin R., Bowman, Sam, Karageorge, Vasilea, Patel, Kaya, Sheng, Zhi, Kelly, Deborah F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585766/ https://www.ncbi.nlm.nih.gov/pubmed/26395823 http://dx.doi.org/10.1038/srep14440 |
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