The C-terminus hot spot region helps in the fibril formation of bacteriophage-associated hyaluronate lyase (HylP2)

The bacteriophage encoded hyaluronate lyases (HylP and HylP2) degrade hyaluronan and other glycosaminoglycans. HylP2 forms a functional fibril under acidic conditions in which its N-terminus is proposed to form the fibrillar core, leading to nucleation and acceleration of fibril formation. Here we r...

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Detalles Bibliográficos
Autores principales: Shukla, Harish, Singh, Sudhir Kumar, Singh, Amit Kumar, Mitra, Kalyan, Akhtar, Md. Sohail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585773/
https://www.ncbi.nlm.nih.gov/pubmed/26395159
http://dx.doi.org/10.1038/srep14429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585773/
https://www.ncbi.nlm.nih.gov/pubmed/26395159
http://dx.doi.org/10.1038/srep14429

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