Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigs

Myostatin (MSTN) is a dominant inhibitor of skeletal muscle development and growth. Mutations in MSTN gene can lead to muscle hypertrophy or double-muscled (DM) phenotype in cattle, sheep, dog and human. However, there has not been reported significant muscle phenotypes in pigs in association with M...

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Detalles Bibliográficos
Autores principales: Qian, Lili, Tang, Maoxue, Yang, Jinzeng, Wang, Qingqing, Cai, Chunbo, Jiang, Shengwang, Li, Hegang, Jiang, Ke, Gao, Pengfei, Ma, Dezun, Chen, Yaoxing, An, Xiaorong, Li, Kui, Cui, Wentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585837/
https://www.ncbi.nlm.nih.gov/pubmed/26400270
http://dx.doi.org/10.1038/srep14435

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