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Opposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression

Macrophages in a tumor microenvironment have been characterized as M1- and M2-polarized subtypes. Here, we discovered the different macrophages’ impacts on lung cancer cell A549. The M2a/M2c subtypes promoted A549 invasion and xenograft tumor growth. The M1 subtype suppressed angiogenesis. M1 enhanc...

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Detalles Bibliográficos
Autores principales:	Yuan, Ang, Hsiao, Yi-Jing, Chen, Hsuan-Yu, Chen, Huei-Wen, Ho, Chao-Chi, Chen, Yu-Yun, Liu, Yi-Chia, Hong, Tsai-Hsia, Yu, Sung-Liang, Chen, Jeremy J.W., Yang, Pan-Chyr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585843/ https://www.ncbi.nlm.nih.gov/pubmed/26399191 http://dx.doi.org/10.1038/srep14273

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