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DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression

Heat shock response (HSR) is an essential host-defense mechanism that is dysregulated in obesity-induced insulin resistance and type 2 diabetes (T2D). Our recent data demonstrated that DNAJB3 was downregulated in obese human subjects and showed negative correlation with inflammatory markers. Neverth...

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Detalles Bibliográficos
Autores principales:	Abu-Farha, Mohamed, Cherian, Preethi, Al-Khairi, Irina, Tiss, Ali, Khadir, Abdelkrim, Kavalakatt, Sina, Warsame, Samia, Dehbi, Mohammed, Behbehani, Kazem, Abubaker, Jehad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585859/ https://www.ncbi.nlm.nih.gov/pubmed/26400768 http://dx.doi.org/10.1038/srep14448

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