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Enhancement of Chiroptical Signals by Circular Differential Mie Scattering of Nanoparticles
We enhance the weak optical signals of small chiral molecules via circular differential Mie scattering (CDMS) of nanoparticles immersed in them. CDMS is the preferential Mie scattering of left- and right-handed circularly polarized light by nanoparticles whose sizes are about the same as the wavelen...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585887/ https://www.ncbi.nlm.nih.gov/pubmed/26403593 http://dx.doi.org/10.1038/srep14463 |
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author | Yoo, SeokJae Park, Q-Han |
author_facet | Yoo, SeokJae Park, Q-Han |
author_sort | Yoo, SeokJae |
collection | PubMed |
description | We enhance the weak optical signals of small chiral molecules via circular differential Mie scattering (CDMS) of nanoparticles immersed in them. CDMS is the preferential Mie scattering of left- and right-handed circularly polarized light by nanoparticles whose sizes are about the same as the wavelength of light. Solving the Mie scattering theory for chiral media, we find that the CDMS signal of the particle is linearly proportional to the chirality parameter κ of the molecules. This linear amplitude enhancement by CDMS of the particle holds, even for large particles, which have a retardation effect. We also demonstrate that the CDMS of a nanoparticle is sensitive to changes of molecular concentration, and that the nanoparticle can be utilized as a chiroptical biosensor detecting the concentration of analyte. We expect that the enhancement of molecular chiroptical signals by CDMS will pave the way for novel chiroptical spectroscopy using nanostructures. |
format | Online Article Text |
id | pubmed-4585887 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-45858872015-09-30 Enhancement of Chiroptical Signals by Circular Differential Mie Scattering of Nanoparticles Yoo, SeokJae Park, Q-Han Sci Rep Article We enhance the weak optical signals of small chiral molecules via circular differential Mie scattering (CDMS) of nanoparticles immersed in them. CDMS is the preferential Mie scattering of left- and right-handed circularly polarized light by nanoparticles whose sizes are about the same as the wavelength of light. Solving the Mie scattering theory for chiral media, we find that the CDMS signal of the particle is linearly proportional to the chirality parameter κ of the molecules. This linear amplitude enhancement by CDMS of the particle holds, even for large particles, which have a retardation effect. We also demonstrate that the CDMS of a nanoparticle is sensitive to changes of molecular concentration, and that the nanoparticle can be utilized as a chiroptical biosensor detecting the concentration of analyte. We expect that the enhancement of molecular chiroptical signals by CDMS will pave the way for novel chiroptical spectroscopy using nanostructures. Nature Publishing Group 2015-09-25 /pmc/articles/PMC4585887/ /pubmed/26403593 http://dx.doi.org/10.1038/srep14463 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Yoo, SeokJae Park, Q-Han Enhancement of Chiroptical Signals by Circular Differential Mie Scattering of Nanoparticles |
title | Enhancement of Chiroptical Signals by Circular Differential Mie Scattering of Nanoparticles |
title_full | Enhancement of Chiroptical Signals by Circular Differential Mie Scattering of Nanoparticles |
title_fullStr | Enhancement of Chiroptical Signals by Circular Differential Mie Scattering of Nanoparticles |
title_full_unstemmed | Enhancement of Chiroptical Signals by Circular Differential Mie Scattering of Nanoparticles |
title_short | Enhancement of Chiroptical Signals by Circular Differential Mie Scattering of Nanoparticles |
title_sort | enhancement of chiroptical signals by circular differential mie scattering of nanoparticles |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585887/ https://www.ncbi.nlm.nih.gov/pubmed/26403593 http://dx.doi.org/10.1038/srep14463 |
work_keys_str_mv | AT yooseokjae enhancementofchiropticalsignalsbycirculardifferentialmiescatteringofnanoparticles AT parkqhan enhancementofchiropticalsignalsbycirculardifferentialmiescatteringofnanoparticles |