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In situ biomarker discovery and label-free molecular histopathological diagnosis of lung cancer by ambient mass spectrometry imaging
Sensitive and spatial exploration of the metabolism of tumors at the metabolome level is highly challenging. In this study, we developed an in situ metabolomics method based on ambient mass spectrometry imaging using air flow-assisted desorption electrospray ionization (AFADESI), which can spatially...
Autores principales: | Li, Tiegang, He, Jiuming, Mao, Xinxin, Bi, Ying, Luo, Zhigang, Guo, Chengan, Tang, Fei, Xu, Xin, Wang, Xiaohao, Wang, Mingrong, Chen, Jie, Abliz, Zeper |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585892/ https://www.ncbi.nlm.nih.gov/pubmed/26404114 http://dx.doi.org/10.1038/srep14089 |
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