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Structural basis of Ac-SDKP hydrolysis by Angiotensin-I converting enzyme

Angiotensin-I converting enzyme (ACE) is a zinc dipeptidylcarboxypeptidase with two active domains and plays a key role in the regulation of blood pressure and electrolyte homeostasis, making it the principal target in the treatment of cardiovascular disease. More recently, the tetrapetide N-acetyl-...

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Detalles Bibliográficos
Autores principales:	Masuyer, Geoffrey, Douglas, Ross G., Sturrock, Edward D., Acharya, K. Ravi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585900/ https://www.ncbi.nlm.nih.gov/pubmed/26403559 http://dx.doi.org/10.1038/srep13742

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