Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation

Pore-forming proteins are weapons often used by bacterial pathogens to breach the membrane barrier of target cells. Despite their critical role in infection important structural aspects of the mechanism of how these proteins assemble into pores remain unknown. Streptococcus pneumoniae is the world’s...

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Detalles Bibliográficos
Autores principales: Lawrence, Sara L., Feil, Susanne C., Morton, Craig J., Farrand, Allison J., Mulhern, Terrence D., Gorman, Michael A., Wade, Kristin R., Tweten, Rodney K., Parker, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585913/
https://www.ncbi.nlm.nih.gov/pubmed/26403197
http://dx.doi.org/10.1038/srep14352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585913/
https://www.ncbi.nlm.nih.gov/pubmed/26403197
http://dx.doi.org/10.1038/srep14352

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