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A RANKL mutant used as an inter-species vaccine for efficient immunotherapy of osteoporosis

Anti-cytokine therapeutic antibodies have been demonstrated to be effective in the treatment of several auto-immune disorders. However, The problems in antibody manufacture and the immunogenicity caused by multiple doses of antibodies inspire people to use auto-cytokine as immunogen to induce anti-c...

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Detalles Bibliográficos
Autores principales: Liu, Changzhen, Zhao, Yunfeng, He, Wen, Wang, Wei, Chen, Yuan, Zhang, Shiqian, Ma, Yijing, Gohda, Jin, Ishida, Takaomi, Walter, Thomas S., Owens, Raymond J., Stuart, David I., Ren, Jingshan, Gao, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585926/
https://www.ncbi.nlm.nih.gov/pubmed/26412210
http://dx.doi.org/10.1038/srep14150

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