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A RANKL mutant used as an inter-species vaccine for efficient immunotherapy of osteoporosis
Anti-cytokine therapeutic antibodies have been demonstrated to be effective in the treatment of several auto-immune disorders. However, The problems in antibody manufacture and the immunogenicity caused by multiple doses of antibodies inspire people to use auto-cytokine as immunogen to induce anti-c...
Autores principales: | Liu, Changzhen, Zhao, Yunfeng, He, Wen, Wang, Wei, Chen, Yuan, Zhang, Shiqian, Ma, Yijing, Gohda, Jin, Ishida, Takaomi, Walter, Thomas S., Owens, Raymond J., Stuart, David I., Ren, Jingshan, Gao, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585926/ https://www.ncbi.nlm.nih.gov/pubmed/26412210 http://dx.doi.org/10.1038/srep14150 |
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