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Functional Analyses of the Toxoplasma gondii DNA Gyrase Holoenzyme: A Janus Topoisomerase with Supercoiling and Decatenation Abilities

A number of important protozoan parasites including those responsible for toxoplasmosis and malaria belong to the phylum Apicomplexa and are characterised by their possession of a relict plastid, the apicoplast. Being required for survival, apicoplasts are potentially useful drug targets and their a...

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Detalles Bibliográficos
Autores principales: Lin, Ting-Yu, Nagano, Soshichiro, Gardiner Heddle, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585971/
https://www.ncbi.nlm.nih.gov/pubmed/26412236
http://dx.doi.org/10.1038/srep14491

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