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Metabolomics insights into chronic kidney disease and modulatory effect of rhubarb against tubulointerstitial fibrosis

Chronic kidney disease (CKD) is a major public health problem worldwide. Rhubarb has been shown to have nephroprotective and anti-fibrotic activities in patients with CKD. However, bioactive fractions and biochemical mechanism of anti-fibrotic properties of rhubarb remain unclear. Here we applied ul...

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Detalles Bibliográficos
Autores principales: Zhang, Zhi-Hao, Wei, Feng, Vaziri, Nosratola D., Cheng, Xian-Long, Bai, Xu, Lin, Rui-Chao, Zhao, Ying-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585987/
https://www.ncbi.nlm.nih.gov/pubmed/26412413
http://dx.doi.org/10.1038/srep14472